By Abramson, David Abramson
Blood Vessels and Lymphatics on Organ structures presents an creation to the overall and the categorical features of blood vessels and lymphatics in organ platforms. It bargains a dependent, multidisciplinary method of the vast box of vascular technology, emphasizing either demonstrated and up to date ideas. those comprise vascular networks similar to these within the pineal, parathyroids, pancreas, adrenals, adipose tissue, and designated senses; and capabilities of vascular endothelium.
The ebook is equipped into components. half One at the normal houses of blood vessels and lymphatics offers with the final facets of the arteries, veins, microcirculation, and lymphatic channels. half discusses the embryologic, morphologic, physiologic, pharmacologic, pathophysiologic, and pathologic features of blood and lymph circulations in all of the vital organ structures.
This ebook was once written for graduate scholars within the components of blood and lymph flow and for complicated examine staff or clinicians looking resources of knowledge on advances in cardiovascular technology.
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ARTERIOSCLEROSIS The category of arteriosclerosis includes a group of changes characterized mainly by stiffening, thickening, and deformation of the arterial wall, due to excessive or disproportionate accumulation of normal and/or abnormal connec tive tissue elements and/or degenerative debris. The common conditions in this group causing primarily intimal changes are diffuse intimal thickening and atherosclerosis. Nonspecific diffuse and local sclerotic changes in the media of large arteries, not directly related to intimal disease, are also frequent and are usually associated with relatively benign alterations in mechanical properties.
In a survey of the literature on the in vitro study of human blood vessels, Bevan (in press) concluded that adrenergic-related properties probably showed less variability than do other features, and virtually all the major attributes of the adrenergic-neuroeffector mechanism established in animal studies have been confirmed in one or more human vascular segments (Fig. 7). However, at present there is insufficient evidence to suggest which of the commonly used laboratory animal species is closest to man.
Although such results have suggested that occlusive thrombi in epicardial vessels may follow rather than precede myocardial infarction (Spain and Bradess, 1970), most recent investigations 1. MORPHOLOGIC AND BIOCHEMICAL ASPECTS O F ARTERIES AND VEINS 43 indicate that an occlusive arterial thrombus on a plaque is probably the signifi cant early event in many, if not most, instances of fatal myocardial infarction (Chandler et al, 1974; Bloor and Ashraf, 1977), (see Section E-2, Chapter 10). Prostacyclin (PGI 2 ), a potent inhibitor of platelet aggregation, is produced in arterial walls and from precursors present in platelets (Moncada and Amezcua, 1979).