Download Capillary Electrophoresis of Nucleic Acids Volume 1 by Mitchelson, Cheng PDF

By Mitchelson, Cheng

An excellent panel of hands-on specialists and builders of CE gear describe in step by step style their top state-of-the-art equipment for the detection and research of DNA mutations and alterations, starting from special DNA loci to whole genomes of organisms. this primary quantity of the set, creation to the Capillary Electrophoresis of Nucleic Acids, covers the sensible and theoretical issues in the back of using capillary electrophoresis for the research of small oligonucleotides and converted nucleotides. besides specified directions making sure prepared reproducibility, those protocols provide time-tested suggestion on instrumentation, sign detection, the capillary surroundings, and the mixing of mass spectrometry with CE. numerous chapters are dedicated to the research of small healing oligonucleotides, nucleosides, and ribonucleotides through CE. The spouse quantity, functional purposes of Capillary Electrophoresis, addresses innovations for high-throughput research of DNA fragments utilizing SNP detection, mutation detection, DNA sequencing tools, and DNA-ligand interactions. entire and updated, the paired volumes of Capillary Electrophoresis of Nucleic Acids provide an authoritative consultant with easy accessibility to speedy, flexible, trustworthy, and strong applied sciences for all these uncomplicated and medical investigators examining DNA version at the present time.

Show description

Read Online or Download Capillary Electrophoresis of Nucleic Acids Volume 1 Introduction to the Capillary Electrophoresis (Methods in Molecular Biology Vol 162) PDF

Best biology books

Dictionary of Developmental Biology and Embryology, Second Edition

A newly revised version of the normal reference for the sector this present day? up to date with new phrases, significant discoveries, major scientists, and illustrationsDevelopmental biology is the examine of the mechanisms of improvement, differentiation, and development in animals and vegetation on the molecular, mobile, and genetic degrees.

Oscillation and Stability of Delay Models in Biology

Environmental edition performs a tremendous position in lots of organic and ecological dynamical platforms. This monograph specializes in the examine of oscillation and the steadiness of hold up types happening in biology. The ebook provides fresh study effects at the qualitative habit of mathematical versions less than diversified actual and environmental stipulations, protecting dynamics together with the distribution and intake of nutrients.

Additional resources for Capillary Electrophoresis of Nucleic Acids Volume 1 Introduction to the Capillary Electrophoresis (Methods in Molecular Biology Vol 162)

Sample text

And Kambara, H. (2001) Selective primer sequencing from a DNA mixture by capillary electrophoresis, in Capillary Electrophoresis of Nucleic Acids, Vol. 2 (Mitchelson, K. R. ), Humana Press, Totowa, NJ, pp. 317–336. 37. , Righetti, P. , and Ferrari, M. (2001) Amplification refractory mutation system analysis of point mutations by capillary electrophoresis, in Capillary Electrophoresis of Nucleic Acids, Vol. 2 (Mitchelson, K. R. ), Humana Press, Totowa, NJ, pp 95–108. 38. , Williams, P. , Williams, S.

Amino Acids 16, 13–19. 69. , and Tura, S. (1998) Detection of bcr-abl transcript in chronic myelogenous leukemia patients by reverse-transcription-polymerase chain reaction and capillary electrophoresis. Haematologica 83, 593–601. 70. Borson, N. , Strausbauch, M. , Wettstein, P. , Oda, R. , Johnston, S. , and Landers, J. P. (1998) Direct quantitation of RNA transcripts by competitive single-tube RT-PCR and capillary electrophoresis. Biotechniques 25, 130–137. 71. , and Brandt, B. H. (1998) Direct quantification of polymerase chain reaction fragments using field-amplified sample injection in capillary zone electrophoresis for gene dosage estimation.

16, 541–546. 14. Righetti, P. G. and Bossi, A. (1998) An isoelectrically trapped enzyme reactor operating in an electric field. Electrophoresis 19, 1075–1080. 15. , Drexhage, K. , Herten, D. , et al. (1998) Multiplex dye DNA sequencing in capillary gel electrophoresis by diode laser-based time-resolved fluorescence detection. Anal. Chem. 70, 4771–4779. 16. Lu, S. , and Yeung, E. S. (1999) Side-entry excitation and detection of square capillary array electrophoresis for DNA sequencing. J. Chromatogr.

Download PDF sample

Rated 4.20 of 5 – based on 33 votes