By Bruce M. Carlson
Grasp the options you want to comprehend with Human Embryology and Developmental Biology. Dr. Bruce M. Carlson's transparent reasons supply an easy-to-follow "road map" in the course of the most modern clinical wisdom, supplying you with a deeper knowing of the major details you must recognize to your classes, tests, and eventually medical perform.
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Extra info for Human Embryology and Developmental Biology (5th Edition)
The cervical epithelium produces glycoprotein-rich cervical mucus, the composition of which varies considerably throughout the menstrual cycle. The differing physical properties of cervical mucus make it easier or more difficult for spermatozoa to penetrate the cervix and find their way into the uterus. Vagina The vagina is a channel for sexual intercourse and serves as the birth canal. It is lined with a stratified squamous epithelium, but the epithelial cells contain deposits of glycogen, which vary in amount throughout the menstrual cycle.
Testosterone is released into the blood and is taken to the Sertoli cells and throughout the body, where it affects a variety of secondary sexual tissues, often after it has been locally converted to dihydrotestosterone. Sertoli cells are stimulated by pituitary FSH via surface FSH receptors and by testosterone from the Leydig cells via cytoplasmic receptors. After FSH stimulation, the Sertoli cells convert some of the testosterone to estrogens (as the granulosa cells in the ovary do). Some of the estrogen diffuses back to the Leydig cells along with a Leydig cell stimulatory factor, which is produced by the Sertoli cells and reaches the Leydig cells by a paracrine (non–blood-borne) mode of secretion (Fig.
Liu K and others: Control of mammalian oocyte growth and early follicular development by the oocyte PI3 kinase pathway: new roles for an old timer, Dev Biol 299:1-11, 2006. Mather JP, Moore A, Li R-H: Activins, inhibins, and follistatins: further thoughts on a growing family of regulators, Proc Soc Exp Biol Med 215:209-222, 1997. Matzuk MM and others: Intercellular communication in the mammalian ovary: oocytes carry the conversation, Science 296:2178-2180, 2002. Mehlmann LM, Jones TLZ, Jaffe LA: Meiotic arrest in the mouse follicle maintained by a Gs protein in the oocyte, Science 297:1343-1345, 2002.