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By G.H. Bourne, J.F. Danielli, K.W. Jeon (Eds.)

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In recent years extracts of normal epidermis have been tested in parallel with extracts obtained by maceration of the tumors themselves. Findings indicate that the epidermal chalone is present in these tumors which presumably synthesize it but in inadequate concentrations. H. SPLEEN As discussed previously (Lozzio, 1973), enlargement of the spleen occurs in the majority of humans and animals suffering from a malignant process. The proliferation of spleen cells is the result of cellular and humoral immune reactions against cancer cells.

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