Download Molecular and Cellular Biology of Neuroprotection in the CNS by Thomas Gillessen, Samantha L. Budd, Stuart A. Lipton PDF

By Thomas Gillessen, Samantha L. Budd, Stuart A. Lipton (auth.), Christian Alzheimer (eds.)

Given the very restricted ability of regeneration within the mind, maintaining neurons which are close to dying is an enormous problem for uncomplicated and scientific neuroscience, with implications for a huge spectrum of acute and protracted neurological and psychiatric illnesses. This booklet brings jointly prime specialists from neurobiology, neurophysiology, neuropharmacology, neuroimmunology and scientific neuroscience to focus on the newest milestones during this speedily evolving box. The e-book will function a reference for either uncomplicated neuroscientists and clinicians attracted to an authoritative replace at the molecular and mobile biology of neuroprotection and its can provide for brand new healing strategies.

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Ann Neurol 1995; 37(1):115-118. 181. Cazevieille C, Muller A, Meynier F et al. Superoxide and nitric oxide cooperation in hypoxia/ reoxygenation-induced neuron injury. Free Radic Biol Med 1993; 14(4):389-395. 182. Dawson VL, Dawson TM, Bartley DA et al. Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures. J Neurosci 1993; 13(6):2651-2661. 183. Dawson VL, Kizushi VM, Huang PL et al. Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice.

Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons. J Neurosci 1993; 13(5):2085-2104. 169. Dumuis A, Sebben M, Haynes L et al. NMDA receptors activate the arachidonic acid cascade system in striatal neurons. Nature 1988; 336(6194):68-70. 170. Chan PH, Fishman RA. Transient formation of superoxide radicals in polyunsaturated fatty acid-induced brain swelling. J Neurochem 1980; 35(4):1004-1007. 171. Lazarewicz JW, Wroblewski JT, Palmer ME et al. Activation of N-methyl-Daspartate-sensitive glutamate receptors stimulates arachidonic acid release in primary cultures of cerebellar granule cells.

J Neurosurg 1992; 77(2):169-184. 38. Choi DW, Rothman SM. The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Annu Rev Neurosci 1990; 13171-182. 39. Hahn JS, Aizenman E, Lipton SA. Central mammalian neurons normally resistant to glutamate toxicity are made sensitive by elevated extracellular Ca 2+: Toxicity is blocked by the N-methyl-D-aspartate antagonist MK-801. Proc Natl Acad Sci USA 1988; 85(17):6556-6560. 40. Ankarcrona M, Dypbukt JM, Bonfoco E et al. Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function.

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